http://archive.nodalpoint.org/2008/07/25/how_history_affects_pattern_matching_inside_the_genome Comments for "How History Affects Pattern Matching Inside The Genome" en http://archive.nodalpoint.org/2008/07/25/how_history_affects_pattern_matching_inside_the_genome <p>In a recent Science magazine article, Löytynoja-Goldman showed that all current Multiple Sequence Alignment algorithms – the bread-and-butter algorithm for biologists studying similarities in genes across different species – completely fail to detect independent insertions in the alignment of sequences, and thus, erroneously mismatches regions of evolutionary volatility. In their improved MSA algorithm, PRANK, they use history itself to improve the performance of this basic algorithm. [<a href="http://boscoh.com/protein/how-history-affects-pattern-matching-inside-the-genome">more...</a>]</p> <br class="clear" /> http://archive.nodalpoint.org/2008/07/25/how_history_affects_pattern_matching_inside_the_genome#comments sequence alignment bioinformatics algorithms evolution phylogenetics Fri, 25 Jul 2008 22:28:33 +0000 bosco 2363 at http://archive.nodalpoint.org