Primer-BLAST combines primer design (using Primer3) and a specificity check with BLAST.
Primer-BLAST combines primer design (using Primer3) and a specificity check with BLAST.
The NIH has published, in 2000, a definition of bioinformatics which is supposed to be the 'official' one:
- http://www.bisti.nih.gov/CompuBioDef.pdf
I partly disagree with that!! Or at least, I think it is incomplete.
Bioinformatics is not only providing services and tools for scientists and for analyzing data.
It is also a scientific discipline, in which you make an hypothesis, you write down your assumptions, you manage to find a way to demonstrate it, and then you share your results with other scientists and confront with them.
Scientists usually share information with collaborators from all around the world. For that purpose, eyeOS (www.eyeos.org) provides an invaluable system to access and share documents, create and save data files or store crucial personal and professional information.
To see eyeOS widely used by scientists all around the world, we initiated the eyeLIMS project ! eyeLIMS is a community-driven project which aims at providing a Free, web-based, Open Source Laboratory Information Management System (LIMS) powered by eyeOS.
After a long hiatus SciView is back with a new interview with Dr Roderic Page from the University of Glasgow. Dr Page is the current Editor in Chief of Syatematic Biology and developer of TreeView(X), the beloved phylogenetic tree visualization software. He was also the editor of the Current Protocols in Bioinformatics.
As usual here is the link.
Enjoy.
I decided to jump on the bandwagon, the same Rosie Redfield jumped because of Pedro: Open Science.
Ever wondered how you might translate trajectories from one Molecular Dynamics package to another? It's a thorny little problem that's afflicted quite a few structural biologists. Here's one ugly solution that I am rather proud of.
The SciView project is back with another interview. This time, Dr Jeremy Squire answered my questions. He is cytogeneticist from the Ontario Cancer Institute, so I tried to get his view on some bioinformatics topics as wet lab scientist. Some great advices and opinions in his answers, not only for bioinformaticians.
http://blindscientist.genedrift.org/2007/06/25/sciview-part-3-interview-...
I was looking for the best way to explain what is blast to people with no background in biology/bioinformatics.
I thought I could to say it's a search engine:
- Blast is the same as google, but for biological sequences instead of search terms.

Finally, NCBI's dbGaP (http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=gap) has started making available data from various genome wide association studies. This will be an awesome resource for understanding the causes of complex diseases.